Rapid test to check/or the presence of anti-deamidated gliadin (anti-DGP) antibodies, lgA and IgG, in the blood, for celiac disease screening

Celiac Disease (CD), also known as “celiac sprue”, is a chronic inflam­matory disorder of the small intestine, produced by the ingestion of dietary gluten products in susceptible people. It is a multifactorial disease, including genetic and environmental factors. Environmental trigger is represented by gluten while the genetic predisposition has been iden­tified in the major histocompatibility complex region which cause the presence of specific antibodies against gluten and its components. Celiac disease is not a rare disorder like previously thought, with a global preva­lence around 1%. The reason of its under recognition is mainly referable to the fact that about half of affected people do not have the classic gastro­intestinal symptoms, but they present nonspecific manifestations of nutritional deficiency or have no symptoms at all.